Our research aims to unravel the basic biological mechanisms of neurobiology and brain disease and to pursue these novel findings to solve major medical problems. This work is defined by five forefront, multidisciplinary research lines, on which our different labs collaborate and interact:
Neuronal and neurodegenerative disease
Neuronal and neurodegenerative disorders are extremely debilitating conditions, affecting millions of people worldwide. For most of these diseases, there are no cures and only symptomatic treatments exist. We are working hard to understand the mechanistic basis of these diseases with the ultimate hope to find cures.
We have uncovered exciting new avenues in the context of Alzheimer’s disease, Parkinson’s disease, ALS and dystonia and together with the translational team of VIB, they are pursuing these targets further. The brain poses specific challenges for drug delivery as it is shielded by a blood brain barrier and our researchers are also developing innovative tools to ensure the drugs we develop can effectively reach their target.