Research themes: Neuronal and neurodegenerative disease

Our research aims to unravel the basic biological mechanisms of neurobiology and brain disease and to pursue these novel findings to solve major medical problems. This work is defined by five forefront, multidisciplinary research lines, on which our different labs collaborate and interact:

Neuronal and neurodegenerative disease

Neuronal and neurodegenerative disorders are extremely debilitating conditions, affecting millions of people worldwide. For most of these diseases, there are no cures and only symptomatic treatments exist. We are working hard to understand the mechanistic basis of these diseases with the ultimate hope to find cures.

We have uncovered exciting new avenues in the context of Alzheimer’s disease, Parkinson’s disease, ALS and dystonia and together with the translational team of VIB, they are pursuing these targets further. The brain poses specific challenges for drug delivery as it is shielded by a blood brain barrier and our researchers are also developing innovative tools to ensure the drugs we develop can effectively reach their target.

 

Labs

STEIN AERTS LAB
Laboratory of computational biology

WIM ANNAERT LAB
Laboratory for membrane trafficking

LUCIA CHAVEZ-GUTIERREZ LAB
Laboratory of proteolytic mechanisms mediating neurodegeneration

BART DE STROOPER LAB
Laboratory for the research of neurodegenerative diseases

ROSE GOODCHILD LAB
Laboratory for dystonia research

ADRIAN LISTON LAB
Translational immunology laboratory

SWITCH LAB
Frederic Rousseau & Joost Schymkowitz

PIERRE VANDERHAEGHEN LAB
Laboratory for stem cell and developmental neurobiology

LUDO VAN DEN BOSCH LAB
Laboratory of neurobiology

PATRIK VERSTREKEN LAB
Laboratory of neuronal communication

THOMAS VOETS LAB
Laboratory of ion channel research

Selected publications

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