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geen vertaling beschikbaar Identical twins light the way for new genetic cause of arthritis

24/01/2019

Identical twin toddlers who presented with severe arthritis helped scientists to identify the first gene mutation that can single-handedly cause a juvenile form of this inflammatory joint disease. By investigating the DNA of individual blood cells of both children and then modelling the genetic defect in a mouse model, the research team led by Adrian Liston (VIB-KU Leuven) was able to unravel the disease mechanism.

geen vertaling beschikbaar Key young talent at VIB

17/12/2018

Claude Libert (VIB-UGent Center for Inflammation Research):  “Steven Timmermans is a bioinformatician in my lab. During his PhD, he has combined two key tasks: providing services to other people in the group (analyzing CHIPSeq, RNASeq and other complex datasets), and building a new research line under the guidance of Yvan Saeys and myself. He has constructed a searchable database (mousepost. be), which collects all key protein polymorphisms in all sequenced mouse strains. This groundbreaking database was recently promoted by Trends in Genetics. What I admire most in Steven is his flexibility in dealing with many different datasets and his perseverance in problem-solving. Bioinformatics expertise is crucial, but to see its daily impact on our projects is amazing. As a PhD student, Steven is first author of publications in PNAS, JCI Insight, Trends in Genetics, Mammalian Genome (twice) and shares first authorship on a PNAS paper.”