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geen vertaling beschikbaar Transplanting human nerve cells into a mouse brain reveals how they wire into brain circuits

21/11/2019

​A team of researchers led by Pierre Vanderhaeghen and Vincent Bonin (VIB-KU Leuven, ULB and NERF) showed how human nerve cells can develop at their own pace, and form highly precise connections with the surrounding mouse brain cells. These findings shed new light on the unique features of the human brain and open new perspectives for brain repair and the study of brain diseases. 

geen vertaling beschikbaar Studying the human brain in mice

30/10/2019

The human brain is a tricky study subject. Brain scans are still limited in resolution and the knowledge they can provide, and in vitro approaches are not yet able to fully replicate the important micro-environment of brain cells. A new method developed by the lab of Bart De Strooper (VIB-KU Leuven Center for Brain & Disease Research) pioneers the transplantation of human microglia cells into mice brains. Their work appears in Nature Neuroscience.

geen vertaling beschikbaar Targeting drugs to the brain

24/09/2019

According to the World Health Organization (WHO), neurological disorders, ranging from epilepsy to Alzheimer’s disease, affect up to one billion people worldwide. These neurological disorders affect people in all countries, irrespective of age, sex, education, or income. The impact of these conditions on healthcare systems across the globe is enormous, and with an aging population in many countries this burden is likely to increase. Patients do not only experience difficulties in the practicalities of life, but also in their emotional and psychological experiences.