Follow us on social media for our latest updates.
A research team led by Joris de Wit at the VIB-KU Leuven Center for Brain & Disease Research has uncovered new molecular players critical for the formation and function of neuronal circuits in the brain. Through proteomic profiling of a specific synapse in the hippocampus, they identified multiple uncharacterized synaptic cell surface proteins, including a new regulator of connectivity.
In this week’s edition of Science, researchers at VIB and the UK DRI highlight the need for a better understanding of the environmental and genetic risks of Alzheimer’s disease. Gene variants should be studied in the right cell types and in the right context, they argue, if we want to make progress in our search for effective therapies.
Every year on World Alzheimer's Day, the French organization: Fondation Recherche Alzheimer honors top European researchers who have made an important contribution to research into the disease. The prize for "most promising young researcher" is awarded this year to two young talents, including Renzo Mancuso: an Argentinian scientist affiliated to VIB and the universities of Leuven and Antwerp.
Researchers at the VIB-KU Leuven Center for Brain & Disease Research uncover how the upregulation of an ion channel called TRPM3 causes hypersensitivity in inflamed tissue. The new findings, published by professor Thomas Voets and his team in eLife, suggest new therapeutic avenues to help patients suffering from chronic pain.
The Science paper by Ryohei Iwata, Pierre Casimir and Pierre Vanderhaeghen on how mitochondrial dynamics in postmitotic cells regulate neurogenesis has been picked up by national news channels.
In this week’s edition of Science, a Belgian team of researchers led by Pierre Vanderhaeghen (VIB-KU Leuven, ULB) finds that mitochondria regulate a key event during brain development: how neural stem cells become nerve cells. Mitochondria influence this cell fate switch during a precise period that is twice as long in humans compared to mice. The seminal findings highlight an unexpected function for mitochondria that may help explain how humans developed a bigger brain during evolution, and how mitochondrial defects lead to neurodevelopmental diseases.
Cancers are extremely heterogeneous. Even within the same tumor, some cells may be more aggressive than others. In the latest issue of Nature Cell Biology, a team of scientists led by Stein Aerts (VIB-KU Leuven Center for Brain & Disease Research) reports how distinct gene regulatory networks drive melanoma skin cancer cells to become more invasive. The findings will inform research into better cancer treatments.
On Sunday July 12th, Wim Annaert embarked on a 2-week biking vacation and fundraising challenge in Bretagne, France. For each kilometer he biked, he pledged to donate € 1 to SAO, the Belgian Alzheimer foundation.
Each year, the European Research Council awards Proof of Concept grants to ERC grant holders who wish to take their ERC research one step further towards application. This year, no less than three VIB principal investigators have received an ERC PoC grant: Prof. Kevin Verstrepen (VIB-KU Leuven Center for Microbiology), Prof. Patrik Verstreken, and Prof. Stein Aerts (both from the VIB-KU Leuven Center for Brain and Disease Research).
A research team led by Bart De Strooper and Mark Fiers at the VIB-KU Leuven Center for Brain & Disease Research in Leuven used pioneering technologies to study in detail what happens in brain cells in the direct vicinity of plaques.