News

Targeting drugs to the brain

24/09/2019

According to the World Health Organization (WHO), neurological disorders, ranging from epilepsy to Alzheimer’s disease, affect up to one billion people worldwide. These neurological disorders affect people in all countries, irrespective of age, sex, education, or income. The impact of these conditions on healthcare systems across the globe is enormous, and with an aging population in many countries this burden is likely to increase. Patients do not only experience difficulties in the practicalities of life, but also in their emotional and psychological experiences.

Do ‘microglia’ hold the key to stop Alzheimer’s disease?

30/04/2019

A Leuven research team led by Prof. Bart De Strooper (VIB-KU Leuven, UK DRI) studied how specialized brain cells called microglia respond to the accumulation of toxic proteins in the brain, a feature typical of Alzheimer’s. The three major disease risk factors for Alzheimer’s—age, sex and genetics—all affect microglia response, raising the possibility that drugs that modulate this response could be useful for treatment.