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Transplanting human nerve cells into a mouse brain reveals how they wire into brain circuits
Human neurons integrate as single cells into the mouse cortex where they display human-like prolonged development and functionally integrate into the visual circuits of the mouse brain. Read all about it in the latest publication of the Vanderhaeghen lab, on collaboration with the Bonin lab at NERF.
Thomas Voets has been awarded with the 2019 Elisabeth Vreven prize by the 'Geneeskundige Stichting Konining Elisabeth' (Queen Elisabeth Medicinal Foundation). For the occassion, GSKE produced this short video (combination of Dutch and English) about the work of Thomas and his team.
Alzheimer lecture by Bart De Strooper
On February 12th, Bart De Strooper gave a public lecture on the challenges and the progress made in the Alzheimer research field. The full talk (in Dutch) is now available with English subtitles and slides in English!
Making the right connections
Condomitti et al. Neuron 2018, brought to you in 1 minute by the one and only Giuseppe Condomitti.
Hsp90 deforms membranes
Elsa Lauwers and Yu-Chun Wang from the Verstreken lab have identified a completely novel function for Hsp90, one of the most common and most studied proteins in our body. In addition to its well-known role as a protein chaperone, Hsp90 stimulates exosome release. These findings shed new light on treatment strategies for both cancer and neurodegenerative diseases.
Read the paper: https://www.sciencedirect.com/science...
Read the press release: http://www.vib.be/en/news/Pages/Hsp90...
Learn more about our research center: https://cbd.vib.be/
HDAC6 inhibition and Charcot-Marie-Tooth
Veronick Benoy, Van Den Bosch lab
HDAC6 inhibition and chemotherapy-induced peripheral neuropathy
Lawrence van Helleputte, PhD student in the Van Den Bosch lab
Alzheimer's and diabetes
Isabel Salas did her PhD in the lab of Bart De Strooper. She summarizes her latest work in 1 minute.
New viral vector for gene delivery to the brain
Melvin Rincon, postdoc in the Holt lab, explains the significance of his findings, recently published in Gene Therapy.
Adhesion molecule ‘barcodes’ shape synaptic identity
Anna Schroeder from the de Wit lab talks about her recent Neuron paper.